
Can Type 2 Diabetes Be Reversed? Experts Explain
A report from Yale School of Medicine notes that Type 2 diabetes can be reversed by reducing insulin resistance.
Type 2 diabetes mellitus (T2DM) is a chronic, life-altering condition affecting more than 35 million Americans. The disease occurs when a person’s cells do not respond to insulin properly, causing high blood sugar levels. Excess glucose in the blood can harm the body, potentially damaging the kidneys, heart and eyes.
Around one in 10 Americans has diabetes, and 90 to 95 percent of them have Type 2, according to the Centers for Disease Control and Prevention.
The disease has long been considered irreversible, but recent research suggests that it may be possible to reverse T2DM or at the very least, put it into a state of remission.
Some medical experts are now comfortable discussing T2DM reversal, noting studies show significant weight loss can restore normal metabolic function, the process by which the body turns food into energy.
A report from Yale School of Medicine (YSM) notes that Type 2 diabetes can be reversed by reducing insulin resistance. Defining research by Gerald I. Shulman, George R. Cowgill Professor of Medicine (endocrinology) and Cellular and Molecular Physiology at YSM, and Kitt Petersen, professor of medicine (endocrinology) at YSM, found that modest weight loss—even as little as 10 percent—can reduce insulin resistance and reverse T2DM. However, the study also found that most people who lost weight later regained it.
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